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Cytoplasmic irradiation results in mitochondrial dysfunction and DRP1-dependent mitochondrial fission

Direct DNA damage is often considered the primary cause of cancer in patients exposed to ionizing radiation or environmental carcinogens. While mitochondria are known to play an important role in radiation-induced cellular response, the mechanisms by which cytoplasmic stimuli modulate mitochondrial...

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Detalhes bibliográficos
Main Authors: Zhang, Bo, Davidson, Mercy M., Zhou, Hongning, Wang, Chunxin, Walker, Winsome F., Hei, Tom K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934017/
https://ncbi.nlm.nih.gov/pubmed/24080278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1411
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