Inhibition of the mitochondrial fission protein dynamin-related protein 1 (Drp1) impairs mitochondrial fission and mitotic catastrophe after x-irradiation

Accumulating evidence suggests that mitochondrial dynamics is crucial for the maintenance of cellular quality control and function in response to various stresses. However, the role of mitochondrial dynamics in cellular responses to ionizing radiation (IR) is still largely unknown. In this study, we...

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Published in:Mol Biol Cell
Main Authors: Yamamori, Tohru, Ike, Satoshi, Bo, Tomoki, Sasagawa, Tomoya, Sakai, Yuri, Suzuki, Motofumi, Yamamoto, Kumiko, Nagane, Masaki, Yasui, Hironobu, Inanami, Osamu
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678018/
https://ncbi.nlm.nih.gov/pubmed/26466676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-03-0181
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