Alterations in c-Myc phenotypes resulting from dynamin-related protein 1 (Drp1)-mediated mitochondrial fission

The c-Myc (Myc) oncoprotein regulates numerous phenotypes pertaining to cell mass, survival and metabolism. Glycolysis, oxidative phosphorylation (OXPHOS) and mitochondrial biogenesis are positively controlled by Myc, with myc−/− rat fibroblasts displaying atrophic mitochondria, structural and funct...

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Detalhes bibliográficos
Main Authors: Sarin, M, Wang, Y, Zhang, F, Rothermund, K, Zhang, Y, Lu, J, Sims-Lucas, S, Beer-Stolz, D, Van Houten, B E, Vockley, J, Goetzman, E S, Anthony Graves, J, Prochownik, E V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702284/
https://ncbi.nlm.nih.gov/pubmed/23764851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.201
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