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Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

Mitochondria in cells comprise a tubulovesicular network shaped continuously by complementary fission and fusion events. The mammalian Drp1 protein plays a key role in fission, while Mfn1, Mfn2, and OPA1 are required for fusion. Shifts in the balance between these opposing processes can occur rapidl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Ann N Y Acad Sci
Main Authors: Chang, Chuang-Rung, Blackstone, Craig
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585781/
https://ncbi.nlm.nih.gov/pubmed/20649536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2010.05629.x
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