A Pilot Microbiota Study in Parkinson’s Disease Patients versus Control Subjects, and Effects of FTY720 and FTY720-Mitoxy Therapies in Parkinsonian and Multiple System Atrophy Mouse Models

BACKGROUND: Parkinson’s disease (PD) and multiple system atrophy (MSA) patients often suffer from gastrointestinal (GI) dysfunction and GI dysbiosis (microbial imbalance). GI dysfunction also occurs in mouse models of PD and MSA. OBJECTIVES: To assess gut dysfunction and dysbiosis in PD subjects as...

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Vydáno v:J Parkinsons Dis
Hlavní autoři: Vidal-Martinez, Guadalupe, Chin, Brandon, Camarillo, Cynthia, Herrera, Gloria V., Yang, Barbara, Sarosiek, Irene, Perez, Ruth G.
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2020
Témata:
Research Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029363/
https://ncbi.nlm.nih.gov/pubmed/31561385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-191693
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