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A genome-wide analysis of targets of macrolide antibiotics in mammalian cells

Macrolide antibiotics, such as erythromycin and josamycin, are natural polyketide products harboring 14- to 16-membered macrocyclic lactone rings to which various sugars are attached. These antibiotics are used extensively in the clinic because of their ability to inhibit bacterial protein synthesis...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Gupta, Amita, Ökesli-Armlovich, Aye, Morgens, David, Bassik, Michael C., Khosla, Chaitan
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029112/
https://ncbi.nlm.nih.gov/pubmed/31915244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010770
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