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Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells
A major challenge of the postgenomic era is to understand how human genes function together in normal and disease states. In microorganisms, high-density genetic interaction (GI) maps are a powerful tool to elucidate gene functions and pathways. We have developed an integrated methodology based on p...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690882/ https://ncbi.nlm.nih.gov/pubmed/23739767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307002110 |
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