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Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells

A major challenge of the postgenomic era is to understand how human genes function together in normal and disease states. In microorganisms, high-density genetic interaction (GI) maps are a powerful tool to elucidate gene functions and pathways. We have developed an integrated methodology based on p...

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Detalhes bibliográficos
Main Authors: Kampmann, Martin, Bassik, Michael C., Weissman, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690882/
https://ncbi.nlm.nih.gov/pubmed/23739767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307002110
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