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Functional genomics platform for pooled screening and mammalian genetic interaction maps

Systematic genetic interaction maps in microorganisms are powerful tools for identifying functional relationships between genes and defining the function of uncharacterized genes. We have recently implemented this strategy in mammalian cells as a two-stage approach. First, genes of interest are robu...

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Detalhes bibliográficos
Main Authors: Kampmann, Martin, Bassik, Michael C., Weissman, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144868/
https://ncbi.nlm.nih.gov/pubmed/24992097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.103
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