A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility

Genetic interaction (GI) maps, comprising pairwise measures of how strongly the function of one gene depends on the presence of a second, have enabled the systematic exploration of gene function in microorganisms. Here, we present a two-stage strategy to construct high-density GI maps in mammalian c...

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Détails bibliographiques
Auteurs principaux: Bassik, Michael C., Kampmann, Martin, Lebbink, Robert Jan, Wang, Shuyi, Hein, Marco Y., Poser, Ina, Weibezahn, Jimena, Horlbeck, Max A., Chen, Siyuan, Mann, Matthias, Hyman, Anthony A., LeProust, Emily M., McManus, Michael T., Weissman, Jonathan S.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652613/
https://ncbi.nlm.nih.gov/pubmed/23394947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.01.030
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