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Methods for studying human sirtuins with activity-based chemical probes

Sirtuins are unique posttranslational modification enzymes that utilize NAD(+) as the co-substrate to remove acyl groups from lysine residues. The deacylation events result in profound biological consequences, from transcription silencing to metabolism regulation. This article focuses on a newly dev...

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Bibliografiska uppgifter
I publikationen:Methods Enzymol
Huvudupphovsmän: Zheng, Song, Wohlfahrt, Jessica, Cohen, Ian, Cen, Yana
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027925/
https://ncbi.nlm.nih.gov/pubmed/32046849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.11.004
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