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Development of Activity-Based Chemical Probes for Human Sirtuins
Sirtuins consume stoichiometric amounts of nicotinamide adenine dinucleotide (NAD(+)) to remove an acetyl group from lysine residues. These enzymes have been implicated in regulating various cellular events and have also been suggested to mediate the beneficial effects of calorie restriction (CR). H...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889851/ https://ncbi.nlm.nih.gov/pubmed/29385333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00754 |
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