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Substrate-Dependent Sensitivity of SIRT1 to Nicotinamide Inhibition
SIRT1 is the most extensively studied human sirtuin with a broad spectrum of endogenous targets. It has been implicated in the regulation of a myriad of cellular events, such as gene transcription, mitochondria biogenesis, insulin secretion as well as glucose and lipid metabolism. From a mechanistic...
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| Publicat a: | Biomolecules |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7922766/ https://ncbi.nlm.nih.gov/pubmed/33670751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020312 |
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