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Trichostatin A Inhibits Deacetylation of Histone H3 and p53 by SIRT6

SIRT6 is an epigenetic modification enzyme that regulates gene transcription through its deacetylase activity. In addition to histone protein, SIRT6 also modify other proteins and enzymes, some of which are central players in metabolic reprogramming and aging process. Therefore, SIRT6 has emerged as...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Wood, Marci, Rymarchyk, Stacia, Zheng, Song, Cen, Yana
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762261/
https://ncbi.nlm.nih.gov/pubmed/29233643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2017.12.009
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