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Trichostatin A Inhibits Deacetylation of Histone H3 and p53 by SIRT6

SIRT6 is an epigenetic modification enzyme that regulates gene transcription through its deacetylase activity. In addition to histone protein, SIRT6 also modify other proteins and enzymes, some of which are central players in metabolic reprogramming and aging process. Therefore, SIRT6 has emerged as...

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Dades bibliogràfiques
Publicat a:Arch Biochem Biophys
Autors principals: Wood, Marci, Rymarchyk, Stacia, Zheng, Song, Cen, Yana
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762261/
https://ncbi.nlm.nih.gov/pubmed/29233643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2017.12.009
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