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Methods for studying human sirtuins with activity-based chemical probes
Sirtuins are unique posttranslational modification enzymes that utilize NAD(+) as the co-substrate to remove acyl groups from lysine residues. The deacylation events result in profound biological consequences, from transcription silencing to metabolism regulation. This article focuses on a newly dev...
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| Vydáno v: | Methods Enzymol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7027925/ https://ncbi.nlm.nih.gov/pubmed/32046849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.11.004 |
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