Cell type-specific mechanisms coupling protease-activated receptor-1 to infectious colitis pathogenesis

BACKGROUND: Protease-activated receptor-1 (PAR-1) plays a major role in multiple disease processes, including colitis. Understanding the mechanisms coupling PAR-1 to disease pathogenesis is complicated by the fact that PAR-1 is broadly expressed across multiple cell types. OBJECTIVE: Determine the s...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Boucher, Alexander A., Rosenfeldt, Leah, Mureb, Duaa, Shafer, Jessica, Sharma, Bal Krishan, Lane, Adam, Crowther, Rebecca R., McKell, Melanie C., Whitt, Jordan, Alenghat, Theresa, Qualls, Joseph, Antoniak, Silvio, Mackman, Nigel, Flick, Matthew J., Steinbrecher, Kris A., Palumbo, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026906/
https://ncbi.nlm.nih.gov/pubmed/31539206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14641
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