Cell type-specific mechanisms coupling protease-activated receptor-1 to infectious colitis pathogenesis

BACKGROUND: Protease-activated receptor-1 (PAR-1) plays a major role in multiple disease processes, including colitis. Understanding the mechanisms coupling PAR-1 to disease pathogenesis is complicated by the fact that PAR-1 is broadly expressed across multiple cell types. OBJECTIVE: Determine the s...

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Publié dans:J Thromb Haemost
Auteurs principaux: Boucher, Alexander A., Rosenfeldt, Leah, Mureb, Duaa, Shafer, Jessica, Sharma, Bal Krishan, Lane, Adam, Crowther, Rebecca R., McKell, Melanie C., Whitt, Jordan, Alenghat, Theresa, Qualls, Joseph, Antoniak, Silvio, Mackman, Nigel, Flick, Matthew J., Steinbrecher, Kris A., Palumbo, Joseph S.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026906/
https://ncbi.nlm.nih.gov/pubmed/31539206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14641
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