A carregar...
Selectivity filter modalities and rapid inactivation of the hERG1 channel
The human ether-á-go-go–related gene (hERG1) channel conducts small outward K(+) currents that are critical for cardiomyocyte membrane repolarization. The gain-of-function mutation N629D at the outer mouth of the selectivity filter (SF) disrupts inactivation and K(+)-selective transport in hERG1, le...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7022143/ https://ncbi.nlm.nih.gov/pubmed/31980532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909196117 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|