Increased PD-1+Tim-3+ exhausted T cells in bone marrow may influence the clinical outcome of patients with AML

BACKGROUND: Altered expression of T cell immune inhibitory receptors may result in immunosuppression and associate with the poor prognosis of leukemia patients in which the leukemic bone marrow (BM) microenvironment may contribute to such immunosuppression. We found higher numbers of programmed deat...

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Detalhes bibliográficos
Publicado no:Biomark Res
Main Authors: Tan, Jiaxiong, Yu, Zhi, Huang, Jingying, Chen, Youchun, Huang, Shuxin, Yao, Danlin, Xu, Ling, Lu, Yuhong, Chen, Shaohua, Li, Yangqiu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020501/
https://ncbi.nlm.nih.gov/pubmed/32082573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-020-0185-8
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