Increased PD-1+Tim-3+ exhausted T cells in bone marrow may influence the clinical outcome of patients with AML

BACKGROUND: Altered expression of T cell immune inhibitory receptors may result in immunosuppression and associate with the poor prognosis of leukemia patients in which the leukemic bone marrow (BM) microenvironment may contribute to such immunosuppression. We found higher numbers of programmed deat...

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Detalles Bibliográficos
Publicado en:Biomark Res
Main Authors: Tan, Jiaxiong, Yu, Zhi, Huang, Jingying, Chen, Youchun, Huang, Shuxin, Yao, Danlin, Xu, Ling, Lu, Yuhong, Chen, Shaohua, Li, Yangqiu
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020501/
https://ncbi.nlm.nih.gov/pubmed/32082573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-020-0185-8
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