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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection
Inhibitory receptors play a crucial role in regulating CD8 T-cell function during chronic viral infection. T-cell Ig- and mucin-domain–containing molecule–3 (Tim-3) is well known to negatively regulate T-cell responses, but its role in CD8 T-cell exhaustion during chronic infection in vivo remains u...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930455/ https://ncbi.nlm.nih.gov/pubmed/20679213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009731107 |
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