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The role of PD-1 and PD-L1 in T-cell immune suppression in patients with hematological malignancies

T-cell activation and dysfunction relies on direct and modulated receptors. Based on their functional outcome, co-signaling molecules can be divided as co-stimulators and co-inhibitors, which positively and negatively control the priming, growth, differentiation and functional maturation of a T-cell...

詳細記述

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書誌詳細
主要な著者: Shi, Li, Chen, Shaohua, Yang, Lijian, Li, Yangqiu
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851976/
https://ncbi.nlm.nih.gov/pubmed/24283718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-74
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