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The role of PD-1 and PD-L1 in T-cell immune suppression in patients with hematological malignancies
T-cell activation and dysfunction relies on direct and modulated receptors. Based on their functional outcome, co-signaling molecules can be divided as co-stimulators and co-inhibitors, which positively and negatively control the priming, growth, differentiation and functional maturation of a T-cell...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3851976/ https://ncbi.nlm.nih.gov/pubmed/24283718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-74 |
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