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Dual sgRNA‐directed gene deletion in basidiomycete Ganoderma lucidum using the CRISPR/Cas9 system

Ganoderma lucidum is an important medicinal mushroom in traditional Chinese medicine. However, the lack of adequate genetic tools has hindered molecular genetic research in and the genetic modification of this species. Here, we report that the presence of an intron is necessary for the efficient exp...

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Detalhes bibliográficos
Publicado no:Microb Biotechnol
Main Authors: Liu, Ke, Sun, Bin, You, Hao, Tu, Jun‐Liang, Yu, Xuya, Zhao, Peng, Xu, Jun‐Wei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017817/
https://ncbi.nlm.nih.gov/pubmed/31958883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1751-7915.13534
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