Tissue-Specific DNA Replication Defects in Drosophila melanogaster Caused by a Meier-Gorlin Syndrome Mutation in Orc4

Meier-Gorlin syndrome is a rare recessive disorder characterized by a number of distinct tissue-specific developmental defects. Genes encoding members of the origin recognition complex (ORC) and additional proteins essential for DNA replication (CDC6, CDT1, GMNN, CDC45, MCM5, and DONSON) are mutated...

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Vydáno v:Genetics
Hlavní autoři: McDaniel, Stephen L., Hollatz, Allison J., Branstad, Anna M., Gaskill, Marissa M., Fox, Catherine A., Harrison, Melissa M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2020
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Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017028/
https://ncbi.nlm.nih.gov/pubmed/31818869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302938
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