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A Meier-Gorlin Syndrome Mutation Impairs the ORC1-Nucleosome Association
Recent studies have identified several genetic mutations within the BAH domain of human Origin Recognition Complex subunit 1 (hORC1(BAH)), including the R105Q mutation, implicated in Meier-Gorlin Syndrome (MGS). However, the pathological role of the hORC1 R105Q mutation remains unclear. In this stud...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654454/ https://ncbi.nlm.nih.gov/pubmed/25689043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5009684 |
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