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Drosophila Model of Meier-Gorlin Syndrome Based on the Mutation in a Conserved C-Terminal Domain of Orc6

Meier-Gorlin syndrome (MGS) is an autosomal recessive disorder characterized by microtia, primordial dwarfism, small ears, and skeletal abnormalities. Patients with MGS often carry mutations in the genes encoding the components of the pre-replicative complex such as Origin Recognition Complex (ORC)...

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Detalhes bibliográficos
Publicado no:Am J Med Genet A
Main Authors: Balasov, Maxim, Akhmetova, Katarina, Chesnokov, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027752/
https://ncbi.nlm.nih.gov/pubmed/26139588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.37214
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