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Humanized Drosophila Model of the Meier-Gorlin Syndrome Reveals Conserved and Divergent Features of the Orc6 Protein

Meier–Gorlin syndrome (MGS) is a rare, autosomal recessive disorder characterized by microtia, primordial dwarfism, small ears, and skeletal abnormalities. Patients with MGS often carry mutations in genes encoding the subunits of the Origin Recognition Complex (ORC), components of the prereplicative...

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Bibliographic Details
Published in:Genetics
Main Authors: Balasov, Maxim, Akhmetova, Katarina, Chesnokov, Igor
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768257/
https://ncbi.nlm.nih.gov/pubmed/33037049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303698
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