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Humanized Drosophila Model of the Meier-Gorlin Syndrome Reveals Conserved and Divergent Features of the Orc6 Protein
Meier–Gorlin syndrome (MGS) is a rare, autosomal recessive disorder characterized by microtia, primordial dwarfism, small ears, and skeletal abnormalities. Patients with MGS often carry mutations in genes encoding the subunits of the Origin Recognition Complex (ORC), components of the prereplicative...
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| Published in: | Genetics |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Genetics Society of America
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7768257/ https://ncbi.nlm.nih.gov/pubmed/33037049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303698 |
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