RhoA-GTPase Modulates Neurite Outgrowth by Regulating the Expression of Spastin and p60-Katanin

RhoA-GTPase (RhoA) is widely regarded as a key molecular switch to inhibit neurite outgrowth by rigidifying the actin cytoskeleton. However, during neurite outgrowth, whether and how microtubule dynamics are regulated by RhoA remains to be elucidated. Herein, CT04 and Y27632 were used to inactivate...

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Publicat a:Cells
Autors principals: Tan, Dandan, Zhang, Haowen, Deng, Junyao, Liu, Jingmin, Wen, Jinkun, Li, Lixia, Wang, Xianghai, Pan, Mengjie, Hu, Xiaofang, Guo, Jiasong
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016723/
https://ncbi.nlm.nih.gov/pubmed/31963385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010230
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