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RhoA-GTPase Modulates Neurite Outgrowth by Regulating the Expression of Spastin and p60-Katanin

RhoA-GTPase (RhoA) is widely regarded as a key molecular switch to inhibit neurite outgrowth by rigidifying the actin cytoskeleton. However, during neurite outgrowth, whether and how microtubule dynamics are regulated by RhoA remains to be elucidated. Herein, CT04 and Y27632 were used to inactivate...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Tan, Dandan, Zhang, Haowen, Deng, Junyao, Liu, Jingmin, Wen, Jinkun, Li, Lixia, Wang, Xianghai, Pan, Mengjie, Hu, Xiaofang, Guo, Jiasong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016723/
https://ncbi.nlm.nih.gov/pubmed/31963385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010230
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