Phospholipase Cδ3 Regulates RhoA/Rho Kinase Signaling and Neurite Outgrowth

Phospholipase Cδ3 (PLCδ3) is a key enzyme regulating phosphoinositide metabolism; however, its physiological function remains unknown. Because PLCδ3 is highly enriched in the cerebellum and cerebral cortex, we examined the role of PLCδ3 in neuronal migration and outgrowth. PLCδ3 knockdown (KD) inhib...

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Detalhes bibliográficos
Main Authors: Kouchi, Zen, Igarashi, Takahiro, Shibayama, Nami, Inanobe, Shunichi, Sakurai, Kazuyuki, Yamaguchi, Hideki, Fukuda, Toshifumi, Yanagi, Shigeru, Nakamura, Yoshikazu, Fukami, Kiyoko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048730/
https://ncbi.nlm.nih.gov/pubmed/21187285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.171223
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