Phospholipase Cδ3 Regulates RhoA/Rho Kinase Signaling and Neurite Outgrowth

Phospholipase Cδ3 (PLCδ3) is a key enzyme regulating phosphoinositide metabolism; however, its physiological function remains unknown. Because PLCδ3 is highly enriched in the cerebellum and cerebral cortex, we examined the role of PLCδ3 in neuronal migration and outgrowth. PLCδ3 knockdown (KD) inhib...

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Bibliografski detalji
Glavni autori: Kouchi, Zen, Igarashi, Takahiro, Shibayama, Nami, Inanobe, Shunichi, Sakurai, Kazuyuki, Yamaguchi, Hideki, Fukuda, Toshifumi, Yanagi, Shigeru, Nakamura, Yoshikazu, Fukami, Kiyoko
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Neurobiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048730/
https://ncbi.nlm.nih.gov/pubmed/21187285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.171223
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