Phospholipase Cδ3 Regulates RhoA/Rho Kinase Signaling and Neurite Outgrowth

Phospholipase Cδ3 (PLCδ3) is a key enzyme regulating phosphoinositide metabolism; however, its physiological function remains unknown. Because PLCδ3 is highly enriched in the cerebellum and cerebral cortex, we examined the role of PLCδ3 in neuronal migration and outgrowth. PLCδ3 knockdown (KD) inhib...

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Bibliographische Detailangaben
Hauptverfasser: Kouchi, Zen, Igarashi, Takahiro, Shibayama, Nami, Inanobe, Shunichi, Sakurai, Kazuyuki, Yamaguchi, Hideki, Fukuda, Toshifumi, Yanagi, Shigeru, Nakamura, Yoshikazu, Fukami, Kiyoko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Neurobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048730/
https://ncbi.nlm.nih.gov/pubmed/21187285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.171223
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