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Calsenilin, a Presenilin Interactor, Regulates RhoA Signaling and Neurite Outgrowth
Calsenilin modulates A-type potassium channels, regulates presenilin-mediated γ-secretase activity, and represses prodynorphin and c-fos genes expression. RhoA is involved in various cellular functions including proliferation, differentiation, migration, transcription, and regulation of the actin cy...
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Publicado no: | Int J Mol Sci |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5979497/ https://ncbi.nlm.nih.gov/pubmed/29652865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041196 |
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