Calsenilin, a Presenilin Interactor, Regulates RhoA Signaling and Neurite Outgrowth

Calsenilin modulates A-type potassium channels, regulates presenilin-mediated γ-secretase activity, and represses prodynorphin and c-fos genes expression. RhoA is involved in various cellular functions including proliferation, differentiation, migration, transcription, and regulation of the actin cy...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Kim, Hee-Jun, Lee, Won-Haeng, Kim, Mo-Jong, Shin, Sunmee, Jang, Byungki, Park, Jae-Bong, Wasco, Wilma, Buxbaum, Joseph D., Kim, Yong-Sun, Choi, Eun-Kyoung
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979497/
https://ncbi.nlm.nih.gov/pubmed/29652865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041196
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