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Phospholipase Cδ3 Regulates RhoA/Rho Kinase Signaling and Neurite Outgrowth

Phospholipase Cδ3 (PLCδ3) is a key enzyme regulating phosphoinositide metabolism; however, its physiological function remains unknown. Because PLCδ3 is highly enriched in the cerebellum and cerebral cortex, we examined the role of PLCδ3 in neuronal migration and outgrowth. PLCδ3 knockdown (KD) inhib...

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Détails bibliographiques
Auteurs principaux: Kouchi, Zen, Igarashi, Takahiro, Shibayama, Nami, Inanobe, Shunichi, Sakurai, Kazuyuki, Yamaguchi, Hideki, Fukuda, Toshifumi, Yanagi, Shigeru, Nakamura, Yoshikazu, Fukami, Kiyoko
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048730/
https://ncbi.nlm.nih.gov/pubmed/21187285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.171223
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