Inhibition of RhoA-Subfamily GTPases Suppresses Schwann Cell Proliferation Through Regulating AKT Pathway Rather Than ROCK Pathway

Inhibiting RhoA-subfamily GTPases by C3 transferase is widely recognized as a prospective strategy to enhance axonal regeneration. When C3 transferase is administered for treating the injured peripheral nerves, Schwann cells (SCs, important glial cells in peripheral nerve) are inevitably impacted an...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Tan, Dandan, Wen, Jinkun, Li, Lixia, Wang, Xianghai, Qian, Changhui, Pan, Mengjie, Lai, Muhua, Deng, Junyao, Hu, Xiaofang, Zhang, Haowen, Guo, Jiasong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255816/
https://ncbi.nlm.nih.gov/pubmed/30515082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00437
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