Transcriptional Signatures of Tau and Amyloid Neuropathology

Alzheimer’s disease (AD) is associated with the intracellular aggregation of hyperphosphorylated tau and the accumulation of β-amyloid in the neocortex. We use transgenic mice harboring human tau (rTg4510) and amyloid precursor protein (J20) mutations to investigate transcriptional changes associate...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: Castanho, Isabel, Murray, Tracey K., Hannon, Eilis, Jeffries, Aaron, Walker, Emma, Laing, Emma, Baulf, Hedley, Harvey, Joshua, Bradshaw, Lauren, Randall, Andrew, Moore, Karen, O’Neill, Paul, Lunnon, Katie, Collier, David A., Ahmed, Zeshan, O’Neill, Michael J., Mill, Jonathan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016505/
https://ncbi.nlm.nih.gov/pubmed/32049030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.063
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