Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue

BACKGROUND: DNA methylation is an important epigenetic mechanism involved in gene regulation, with alterations in DNA methylation in the nuclear genome being linked to numerous complex diseases. Mitochondrial DNA methylation is a phenomenon that is receiving ever-increasing interest, particularly in...

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Bibliographic Details
Published in:Clin Epigenetics
Main Authors: Devall, Matthew, Smith, Rebecca G., Jeffries, Aaron, Hannon, Eilis, Davies, Matthew N., Schalkwyk, Leonard, Mill, Jonathan, Weedon, Michael, Lunnon, Katie
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415779/
https://ncbi.nlm.nih.gov/pubmed/28473874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0337-3
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