Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer’s disease brain

Although mutations within the TREM2 gene have been robustly associated with Alzheimer’s disease, it is not known whether alterations in the regulation of this gene are also involved in pathogenesis. Here we present data demonstrating increased DNA methylation in the superior temporal gyrus in AD bra...

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Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Smith, Adam, Smith, Rebecca G., Condliffe, Daniel, Hannon, Eilis, Schalkwyk, Leonard, Mill, Jonathan, Lunnon, Katie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747529/
https://ncbi.nlm.nih.gov/pubmed/27522519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.07.008
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