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Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1β Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration

Chronic neuroinflammation contributes to the pathogenesis of Parkinson’s disease (PD). However, cellular and molecular mechanisms by which chronic neuroinflammation is formed and maintained remain elusive. This study aimed to explore detailed mechanisms by which anti-inflammatory cytokine interleuki...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Gao, Yun, Tu, Dezhen, Yang, Ru, Chu, Chun-Hsien, Hong, Jau-Shyong, Gao, Hui-Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013455/
https://ncbi.nlm.nih.gov/pubmed/31940754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020465
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