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Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1β Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration

Chronic neuroinflammation contributes to the pathogenesis of Parkinson’s disease (PD). However, cellular and molecular mechanisms by which chronic neuroinflammation is formed and maintained remain elusive. This study aimed to explore detailed mechanisms by which anti-inflammatory cytokine interleuki...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Gao, Yun, Tu, Dezhen, Yang, Ru, Chu, Chun-Hsien, Hong, Jau-Shyong, Gao, Hui-Ming
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013455/
https://ncbi.nlm.nih.gov/pubmed/31940754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020465
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