Thrombospondin-1 Exacerbates Acute Liver Failure and Hepatic Encephalopathy Pathology in Mice by Activating Transforming Growth Factor β1

Severe hepatic insults can lead to acute liver failure and hepatic encephalopathy (HE). Transforming growth factor β1 (TGFβ1) has been shown to contribute to HE during acute liver failure; however, TGFβ1 must be activated to bind its receptor and generate downstream effects. One protein that can act...

Full description

Saved in:
Bibliographic Details
Published in:Am J Pathol
Main Authors: Jefferson, Brandi, Ali, Malaika, Grant, Stephanie, Frampton, Gabriel, Ploof, Michaela, Andry, Sarah, DeMorrow, Sharon, McMillin, Matthew
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013272/
https://ncbi.nlm.nih.gov/pubmed/31734229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.10.003
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items