Thrombospondin-1 Exacerbates Acute Liver Failure and Hepatic Encephalopathy Pathology in Mice by Activating Transforming Growth Factor β1

Severe hepatic insults can lead to acute liver failure and hepatic encephalopathy (HE). Transforming growth factor β1 (TGFβ1) has been shown to contribute to HE during acute liver failure; however, TGFβ1 must be activated to bind its receptor and generate downstream effects. One protein that can act...

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Bibliografiset tiedot
Julkaisussa:Am J Pathol
Päätekijät: Jefferson, Brandi, Ali, Malaika, Grant, Stephanie, Frampton, Gabriel, Ploof, Michaela, Andry, Sarah, DeMorrow, Sharon, McMillin, Matthew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013272/
https://ncbi.nlm.nih.gov/pubmed/31734229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.10.003
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