Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice

Hepatic encephalopathy (HE) is a neuropsychiatric complication that occurs due to deteriorating hepatic function and this syndrome influences patient quality of life, clinical management strategies and survival. During acute liver failure, circulating bile acids increase due to a disruption of the e...

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Gepubliceerd in:Front Cell Neurosci
Hoofdauteurs: McMillin, Matthew, Frampton, Gabriel, Grant, Stephanie, Khan, Shamyal, Diocares, Juan, Petrescu, Anca, Wyatt, Amy, Kain, Jessica, Jefferson, Brandi, DeMorrow, Sharon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496949/
https://ncbi.nlm.nih.gov/pubmed/28725183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00191
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