Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice

Hepatic encephalopathy (HE) is a neuropsychiatric complication that occurs due to deteriorating hepatic function and this syndrome influences patient quality of life, clinical management strategies and survival. During acute liver failure, circulating bile acids increase due to a disruption of the e...

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Udgivet i:Front Cell Neurosci
Main Authors: McMillin, Matthew, Frampton, Gabriel, Grant, Stephanie, Khan, Shamyal, Diocares, Juan, Petrescu, Anca, Wyatt, Amy, Kain, Jessica, Jefferson, Brandi, DeMorrow, Sharon
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496949/
https://ncbi.nlm.nih.gov/pubmed/28725183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00191
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