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Analysis of Site-specific Phosphorylation of PTEN using Enzyme-Catalyzed Expressed Protein Ligation

The activity and localization of PTEN, a tumor suppressor lipid phosphatase that converts the phospholipid PIP3 to PIP2, is governed in part by phosphorylation on a cluster of four Ser and Thr residues near the C-terminus. Prior enzymatic characterization of the four mono-phosphorylated (1p) PTENs u...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Henager, Samuel H., Henriquez, Stephanie, Dempsey, Daniel R., Cole, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012368/
https://ncbi.nlm.nih.gov/pubmed/31206229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900316
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