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Protein chemical approaches to understanding PTEN lipid phosphatase regulation
Since the discovery of C-tail phosphorylation of PTEN almost 20 years ago, much progress has been made in understanding its regulatory influences on the cellular function of PTEN. Phosphorylation of Ser380, Thr382, Thr383, and Ser385 drives a PTEN conformational change from an open to closed state w...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6231048/ https://ncbi.nlm.nih.gov/pubmed/30149868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.05.007 |
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