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Actin polymerization regulates recruitment of Nck to CD3ε upon T‐cell receptor triggering

Following T‐cell antigen receptor (TCR) engagement, rearrangement of the actin cytoskeleton supports intracellular signal transduction and T‐cell activation. The non‐catalytic region of the tyrosine kinase (Nck) molecule is an adapter protein implicated in TCR‐induced actin polymerization. Further,...

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Detalles Bibliográficos
Publicado en:Immunology
Main Authors: Wipa, Piyamaporn, Paensuwan, Pussadee, Ngoenkam, Jatuporn, Woessner, Nadine M., Minguet, Susana, Schamel, Wolfgang W., Pongcharoen, Sutatip
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011646/
https://ncbi.nlm.nih.gov/pubmed/31674657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13146
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