Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation

BACKGROUND: Signalling by the T cell antigen receptor (TCR) results in the activation of T lymphocytes. Nck1 and Nck2 are two highly related adaptor proteins downstream of the TCR that each contains three SH3 and one SH2 domains. Their individual functions and the roles of their SH3 domains in human...

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Main Authors: Ngoenkam, Jatuporn, Paensuwan, Pussadee, Preechanukul, Kanlaya, Khamsri, Boonruang, Yiemwattana, Ichaya, Beck-García, Esmeralda, Minguet, Susana, Schamel, Wolfgang WA, Pongcharoen, Sutatip
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977700/
https://ncbi.nlm.nih.gov/pubmed/24670066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-21
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