Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation

BACKGROUND: Signalling by the T cell antigen receptor (TCR) results in the activation of T lymphocytes. Nck1 and Nck2 are two highly related adaptor proteins downstream of the TCR that each contains three SH3 and one SH2 domains. Their individual functions and the roles of their SH3 domains in human...

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Hlavní autoři: Ngoenkam, Jatuporn, Paensuwan, Pussadee, Preechanukul, Kanlaya, Khamsri, Boonruang, Yiemwattana, Ichaya, Beck-García, Esmeralda, Minguet, Susana, Schamel, Wolfgang WA, Pongcharoen, Sutatip
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977700/
https://ncbi.nlm.nih.gov/pubmed/24670066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-21
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