Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation

BACKGROUND: Signalling by the T cell antigen receptor (TCR) results in the activation of T lymphocytes. Nck1 and Nck2 are two highly related adaptor proteins downstream of the TCR that each contains three SH3 and one SH2 domains. Their individual functions and the roles of their SH3 domains in human...

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Autors principals: Ngoenkam, Jatuporn, Paensuwan, Pussadee, Preechanukul, Kanlaya, Khamsri, Boonruang, Yiemwattana, Ichaya, Beck-García, Esmeralda, Minguet, Susana, Schamel, Wolfgang WA, Pongcharoen, Sutatip
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977700/
https://ncbi.nlm.nih.gov/pubmed/24670066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-21
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