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Selected signalling proteins recruited to the T‐cell receptor–CD3 complex

The T‐cell receptor (TCR)–CD3 complex, expressed on T cells, determines the outcome of a T‐cell response. It consists of the TCR‐αβ heterodimer and the non‐covalently associated signalling dimers of CD3εγ, CD3εδ and CD3ζζ. TCR‐αβ binds specifically to a cognate peptide antigen bound to an MHC molecu...

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Bibliografske podrobnosti
izdano v:Immunology
Main Authors: Ngoenkam, Jatuporn, Schamel, Wolfgang W., Pongcharoen, Sutatip
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721247/
https://ncbi.nlm.nih.gov/pubmed/28771705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12809
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