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Actin polymerization regulates recruitment of Nck to CD3ε upon T‐cell receptor triggering

Following T‐cell antigen receptor (TCR) engagement, rearrangement of the actin cytoskeleton supports intracellular signal transduction and T‐cell activation. The non‐catalytic region of the tyrosine kinase (Nck) molecule is an adapter protein implicated in TCR‐induced actin polymerization. Further,...

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Dettagli Bibliografici
Pubblicato in:Immunology
Autori principali: Wipa, Piyamaporn, Paensuwan, Pussadee, Ngoenkam, Jatuporn, Woessner, Nadine M., Minguet, Susana, Schamel, Wolfgang W., Pongcharoen, Sutatip
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011646/
https://ncbi.nlm.nih.gov/pubmed/31674657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13146
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